A seminal paper by Miller and Brody [1] clearly laid the general framework on why we should abandon the term "clinical equipoise" in research. Their paper argued that the concept of equipoise (also ...
RCTs incorporate several methodological characteristics intended to maximize the validity of conclusions about the efficacy and safety of the intervention under study. 1 First, they employ a ...
NOTHING I have seen this racing year was quite so amazing as the victory of Equipoise in the Pimlico Futurity. It is not unusual for a horse to win after getting off to a poor start, but I don’t think ...
In this issue of the Journal of Clinical Oncology, Saltz et al 1 report the results of Cancer and Leukemia Group B (CALGB) 89803, a prospective randomized phase III trial of adjuvant therapy for ...
Long-Term Follow-Up of the Prospective Randomized AATT Study (Autologous or Allogeneic Transplantation in Patients With Peripheral T-Cell Lymphoma) Novel cancer drugs can produce higher and more ...
Clinical equipoise, or uncertainty about which treatment is best for a patient, is widely viewed as essential for an ethical RCT. The authors argue that clinical trials that violate equipoise are ...
In the fifth running of the Whitney Stakes (4,000 added, 3-year-olds and up, 1 1/4 miles) at Saratoga Race Course Aug. 13 (1932), Equipoise went through the formality of scoring his ninth win of the ...
Dr. Adil Shamoo does an admirable job of debunking the legitimacy of using "equipoise" to justify the conduct of phase 1 clinical trials and, by extension, phase 2 and 3 clinical trials. [1] To the ...
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